Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ORGANIC CHEMISTRY II | PHA2113086 | Fall Semester | 3+0 | 3 | 5 |
| Course Program | Cuma 13:30-14:15 Cuma 14:30-15:15 Cuma 15:30-16:15 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Mine YARIM YÜKSEL |
| Name of Lecturer(s) | Lect.Dr. İsmail FİDAN |
| Assistant(s) | |
| Aim | To explain the reaction types, synthesis and possible reactions of organic compounds |
| Course Content | This course contains; 1. Alkane reactions and radicalic reactions,2. Alkene and alkyne reactions: elimination and addition reactions,3. Reactions of alkyl halides and alcohols; nucleophilic substitution reactions,4. Reactions of alkyl halides and alcohols; nucleophilic substitution reactions (continued),5. Reactions of aromatic compounds, aromatic electrophilic substitution reactions,6. Reactions of aromatic compounds, aromatic electrophilic substitution reactions (continued),7. The reactions through carbonyl groups,8. The reactions through carbonyl groups (continued),9. The reactions through alfa position of carbonyl groups,10. The reactions of the carboxylic acid and its derivatives,11. Reactions of amines,12. Nomenclature and general synthesis of heterocyclic compounds,13. Nomenclature and general synthesis of heterocyclic compounds (continued),14. Name reactions. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 3.1.explain addition reactions to aldehydes and ketones | 16, 18, 19, 9 | A |
| 1. Classify reaaction types. | 16, 18, 9 | A |
| 1.1. Example radicalic reactions. | 16, 18, 9 | A |
| 1.2. Explain addition and elimination reactions | 16, 18, 9 | A |
| 1.3. Explain nucleophilic and electrophilic substitution reactions and rearrangement reactions. | 16, 18, 9 | A |
| 2. interprete synthesis reactions of organic compounds. | 16, 18, 19, 9 | A |
| 2.1. explain elimination and addition reactions of alkenes and alkynes. | 16, 18, 19, 9 | A |
| 2.2. Explain nucleophilic substitution reactions of alcohols and alkyl halides. | 16, 18, 19, 9 | A |
| 2.3. explain electrophilic substitution reactions of aromatic compounds | 16, 18, 19, 9 | A |
| 3. classify the reactions of carbonyl containing compounds | 16, 18, 19, 9 | A |
| 3.2. give reaction example on alpha carbons of carbonyl group. | 16, 18, 19, 9 | A |
| 3.3. explain reactions related to amino and carboxyl group. | 16, 18, 19, 9 | A |
| 4. Define chemistry of heterocyclic systems. | 16, 18, 19, 9 | A |
| 4.1. Narrate nomenclature of heterocyclic compounds. | 16, 18, 19, 9 | A |
| 4.2. Classify synthesis reactions of heterocyclic compounds. | 16, 18, 19, 9 | A |
| 4.3. Recognizes some name reactions. | 16, 18, 19, 9 | A |
| Teaching Methods: | 16: Question - Answer Technique, 18: Micro Teaching Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | 1. Alkane reactions and radicalic reactions | Reading the reference book |
| 2 | 2. Alkene and alkyne reactions: elimination and addition reactions | Reading the reference book |
| 3 | 3. Reactions of alkyl halides and alcohols; nucleophilic substitution reactions | Reading the reference book |
| 4 | 4. Reactions of alkyl halides and alcohols; nucleophilic substitution reactions (continued) | Reading the reference book |
| 5 | 5. Reactions of aromatic compounds, aromatic electrophilic substitution reactions | Reading the reference book |
| 6 | 6. Reactions of aromatic compounds, aromatic electrophilic substitution reactions (continued) | Reading the reference book |
| 7 | 7. The reactions through carbonyl groups | Reading the reference book |
| 8 | 8. The reactions through carbonyl groups (continued) | Reading the reference book |
| 9 | 9. The reactions through alfa position of carbonyl groups | Reading the reference book |
| 10 | 10. The reactions of the carboxylic acid and its derivatives | Reading the reference book |
| 11 | 11. Reactions of amines | Reading the reference book |
| 12 | 12. Nomenclature and general synthesis of heterocyclic compounds | Reading the reference book |
| 13 | 13. Nomenclature and general synthesis of heterocyclic compounds (continued) | Reading the reference book |
| 14 | 14. Name reactions | Reading the reference book |
| Resources |
| 1. Solomons’ Organic Chemistry |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | ||||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | ||||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | ||||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | ||||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | ||||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | ||||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | ||||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | ||||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | ||||||
| 14 | PQ-14. Record and document all professional activities and applications. | ||||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | ||||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | ||||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | ||||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 14 | 3 | 42 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 1 | 16 | 16 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 25 | 25 | |||
| General Exam | 1 | 25 | 25 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 150 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(150/30) | 5 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ORGANIC CHEMISTRY II | PHA2113086 | Fall Semester | 3+0 | 3 | 5 |
| Course Program | Cuma 13:30-14:15 Cuma 14:30-15:15 Cuma 15:30-16:15 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Mine YARIM YÜKSEL |
| Name of Lecturer(s) | Lect.Dr. İsmail FİDAN |
| Assistant(s) | |
| Aim | To explain the reaction types, synthesis and possible reactions of organic compounds |
| Course Content | This course contains; 1. Alkane reactions and radicalic reactions,2. Alkene and alkyne reactions: elimination and addition reactions,3. Reactions of alkyl halides and alcohols; nucleophilic substitution reactions,4. Reactions of alkyl halides and alcohols; nucleophilic substitution reactions (continued),5. Reactions of aromatic compounds, aromatic electrophilic substitution reactions,6. Reactions of aromatic compounds, aromatic electrophilic substitution reactions (continued),7. The reactions through carbonyl groups,8. The reactions through carbonyl groups (continued),9. The reactions through alfa position of carbonyl groups,10. The reactions of the carboxylic acid and its derivatives,11. Reactions of amines,12. Nomenclature and general synthesis of heterocyclic compounds,13. Nomenclature and general synthesis of heterocyclic compounds (continued),14. Name reactions. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 3.1.explain addition reactions to aldehydes and ketones | 16, 18, 19, 9 | A |
| 1. Classify reaaction types. | 16, 18, 9 | A |
| 1.1. Example radicalic reactions. | 16, 18, 9 | A |
| 1.2. Explain addition and elimination reactions | 16, 18, 9 | A |
| 1.3. Explain nucleophilic and electrophilic substitution reactions and rearrangement reactions. | 16, 18, 9 | A |
| 2. interprete synthesis reactions of organic compounds. | 16, 18, 19, 9 | A |
| 2.1. explain elimination and addition reactions of alkenes and alkynes. | 16, 18, 19, 9 | A |
| 2.2. Explain nucleophilic substitution reactions of alcohols and alkyl halides. | 16, 18, 19, 9 | A |
| 2.3. explain electrophilic substitution reactions of aromatic compounds | 16, 18, 19, 9 | A |
| 3. classify the reactions of carbonyl containing compounds | 16, 18, 19, 9 | A |
| 3.2. give reaction example on alpha carbons of carbonyl group. | 16, 18, 19, 9 | A |
| 3.3. explain reactions related to amino and carboxyl group. | 16, 18, 19, 9 | A |
| 4. Define chemistry of heterocyclic systems. | 16, 18, 19, 9 | A |
| 4.1. Narrate nomenclature of heterocyclic compounds. | 16, 18, 19, 9 | A |
| 4.2. Classify synthesis reactions of heterocyclic compounds. | 16, 18, 19, 9 | A |
| 4.3. Recognizes some name reactions. | 16, 18, 19, 9 | A |
| Teaching Methods: | 16: Question - Answer Technique, 18: Micro Teaching Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | 1. Alkane reactions and radicalic reactions | Reading the reference book |
| 2 | 2. Alkene and alkyne reactions: elimination and addition reactions | Reading the reference book |
| 3 | 3. Reactions of alkyl halides and alcohols; nucleophilic substitution reactions | Reading the reference book |
| 4 | 4. Reactions of alkyl halides and alcohols; nucleophilic substitution reactions (continued) | Reading the reference book |
| 5 | 5. Reactions of aromatic compounds, aromatic electrophilic substitution reactions | Reading the reference book |
| 6 | 6. Reactions of aromatic compounds, aromatic electrophilic substitution reactions (continued) | Reading the reference book |
| 7 | 7. The reactions through carbonyl groups | Reading the reference book |
| 8 | 8. The reactions through carbonyl groups (continued) | Reading the reference book |
| 9 | 9. The reactions through alfa position of carbonyl groups | Reading the reference book |
| 10 | 10. The reactions of the carboxylic acid and its derivatives | Reading the reference book |
| 11 | 11. Reactions of amines | Reading the reference book |
| 12 | 12. Nomenclature and general synthesis of heterocyclic compounds | Reading the reference book |
| 13 | 13. Nomenclature and general synthesis of heterocyclic compounds (continued) | Reading the reference book |
| 14 | 14. Name reactions | Reading the reference book |
| Resources |
| 1. Solomons’ Organic Chemistry |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | ||||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | ||||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | ||||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | ||||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | ||||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | ||||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | ||||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | ||||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | ||||||
| 14 | PQ-14. Record and document all professional activities and applications. | ||||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | ||||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | ||||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | ||||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |