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Course Description

CourseCodeSemesterT+P (Hour)CreditECTS
TOXICOLOGYECF4246800Spring Semester3+035
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of CourseTurkish
Course LevelFirst Cycle (Bachelor's Degree)
Course TypeRequired
Course CoordinatorProf.Dr. Gülden Zehra OMURTAG
Name of Lecturer(s)Assist.Prof. Sezgin AYDEMİR, Assist.Prof. Ayfer BECEREN
Assistant(s)
AimThe aim of this course is to inform the general toxicological concepts, toxic dose, entry ways into the body of poisons, toxicokinetic and toxicodinamy, systematic toxicology and toxicological examination of chemicals, general principles of treatment in poisoning, allergy, genetic factors and advers drug reactions.
Course ContentThis course contains; 1.Introduction to toxicology, dose, entry ways into the body and absorption of poisons.,2. Distribution, accumulation, biotransformation of toxicants and factors affecting biotransformation. Excretion of poisons.,3. Toxic effect mechanisms (Toxicodynamics),4. Systemic toxicology. Toxicological analysis of xenobiotics. Assessment and risk analysis of the test results. Factors affecting toxicity.,5. Toxic effects of organic solvents. Biomarkers.,6. Toxic effects from herbal and animal poisons,7. Mycotoxins and toxic effects of mycotoxins. Mushroom poisoning and treatment of mushroom poisoning,8. First aid in acute poisoning, antidotes and treatment principles,9. Toxicity of pesticides, and treatment of pesticides poisoning,10. Drug toxicity. Treatment of acute poisoning with drugs,11. Toxicity of metals.,12. Carbon monoxide poisoning and treatment of carbon monoxide poisoning. Cyanide poisoning and treatment of cyanide poisoning.,13.. Pharmacogenetics, toxicogenomics, the difference between pharmacogenetics and allergic reactions.,14. Adverse drug reactions and pharmacovigilance practices in Turkey.
Dersin Öğrenme KazanımlarıTeaching MethodsAssessment Methods
1. Defines toxicology and the concept of dose.13, 16, 9A
1.1. Evaluates the ways poisons enter the body and their absorption.13, 16, 9A
1.2. Evaluates the distribution of poisons, their accumulation in the body, biotransformation and factors affecting biotransformation, and excretion of poisons.13, 16, 9A
2. Explain toxicodynamics and toxicokinetics.16, 9A
2.1. Explains systemic toxicology.16, 9A
3. Compares and evaluates poisons of plant and animal origin and their toxic effects. 13, 16, 9A
3.1. Evaluate mycotoxins and their toxic effects. 13, 16, 9A
3.2. Comments on mushroom poisoning and its treatments.13, 16, 9A
3.3. Explains pesticides and their toxic effects and treatment steps.13, 16, 9A
4. Classifies the symptoms and treatment methods of poisoning by xenobiotics.16, 9A
4.1. Evaluates acute and chronic toxicity symptoms of metals.16, 9A
4.2. Evaluate the toxic effects of organic solvents. 16, 9A
4.3. Evaluates the treatment method in cases of drug poisoning according to the symptoms and degree of poisoning.16, 9A
5. Explains first aid steps and antidotes in acute poisoning.13, 16, 9A
6. Defines the concepts of pharmacogenetics, toxicogenomics and pharmacogenetics. 13, 16, 9A
6.1. Defines the concepts of adverse effects and pharmacovigilance.13, 16, 9A
Teaching Methods:13: Case Study Method, 16: Question - Answer Technique, 9: Lecture Method
Assessment Methods:A: Traditional Written Exam

Course Outline

OrderSubjectsPreliminary Work
11.Introduction to toxicology, dose, entry ways into the body and absorption of poisons.1
22. Distribution, accumulation, biotransformation of toxicants and factors affecting biotransformation. Excretion of poisons.1
33. Toxic effect mechanisms (Toxicodynamics)1
44. Systemic toxicology. Toxicological analysis of xenobiotics. Assessment and risk analysis of the test results. Factors affecting toxicity.1,2
55. Toxic effects of organic solvents. Biomarkers.1
66. Toxic effects from herbal and animal poisons1
77. Mycotoxins and toxic effects of mycotoxins. Mushroom poisoning and treatment of mushroom poisoning1
88. First aid in acute poisoning, antidotes and treatment principles1,2
99. Toxicity of pesticides, and treatment of pesticides poisoning1
1010. Drug toxicity. Treatment of acute poisoning with drugs1
1111. Toxicity of metals.1
1212. Carbon monoxide poisoning and treatment of carbon monoxide poisoning. Cyanide poisoning and treatment of cyanide poisoning.1
1313.. Pharmacogenetics, toxicogenomics, the difference between pharmacogenetics and allergic reactions.1
1414. Adverse drug reactions and pharmacovigilance practices in Turkey1
Resources
1. The course note. 2. Nevin VURAL -TOKSİKOLOJİ, Ankara Üniversitesi Yayınları, Ankara.1996. (e-book)

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
NoProgram QualificationContribution Level
12345
1
PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences.
X
2
PQ-2. Have advanced knowledge in APIs and DPs.
3
PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field.
4
PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient.
5
PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems.
6
PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences.
7
PQ-7. Provide solutions to the professional issues using scientific knowledge and data.
8
PQ-8. Perform identification, quality control and standardization of the drug products.
9
PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments.
10
PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations.
X
11
PQ-11. Clearly show signs of adoption of life-long learning and openness to further development.
X
12
PQ-12. Critically evaluate their knowledge in pharmaceutical sciences.
X
13
PQ-13. Closely follow and evaluate the national and international professional developments.
X
14
PQ-14. Record and document all professional activities and applications.
X
15
PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public.
X
16
PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences.
17
PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products.
18
PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs.
19
PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship.
20
PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards.
21
PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues.
X

Assessment Methods

Contribution LevelAbsolute Evaluation
Rate of Midterm Exam to Success 40
Rate of Final Exam to Success 60
Total 100
ECTS / Workload Table
ActivitiesNumber ofDuration(Hour)Total Workload(Hour)
Course Hours14342
Guided Problem Solving000
Resolution of Homework Problems and Submission as a Report5210
Term Project000
Presentation of Project / Seminar11010
Quiz000
Midterm Exam13030
General Exam16060
Performance Task, Maintenance Plan000
Total Workload(Hour)152
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(152/30)5
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.

Detail Informations of the Course

Course Description

CourseCodeSemesterT+P (Hour)CreditECTS
TOXICOLOGYECF4246800Spring Semester3+035
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of CourseTurkish
Course LevelFirst Cycle (Bachelor's Degree)
Course TypeRequired
Course CoordinatorProf.Dr. Gülden Zehra OMURTAG
Name of Lecturer(s)Assist.Prof. Sezgin AYDEMİR, Assist.Prof. Ayfer BECEREN
Assistant(s)
AimThe aim of this course is to inform the general toxicological concepts, toxic dose, entry ways into the body of poisons, toxicokinetic and toxicodinamy, systematic toxicology and toxicological examination of chemicals, general principles of treatment in poisoning, allergy, genetic factors and advers drug reactions.
Course ContentThis course contains; 1.Introduction to toxicology, dose, entry ways into the body and absorption of poisons.,2. Distribution, accumulation, biotransformation of toxicants and factors affecting biotransformation. Excretion of poisons.,3. Toxic effect mechanisms (Toxicodynamics),4. Systemic toxicology. Toxicological analysis of xenobiotics. Assessment and risk analysis of the test results. Factors affecting toxicity.,5. Toxic effects of organic solvents. Biomarkers.,6. Toxic effects from herbal and animal poisons,7. Mycotoxins and toxic effects of mycotoxins. Mushroom poisoning and treatment of mushroom poisoning,8. First aid in acute poisoning, antidotes and treatment principles,9. Toxicity of pesticides, and treatment of pesticides poisoning,10. Drug toxicity. Treatment of acute poisoning with drugs,11. Toxicity of metals.,12. Carbon monoxide poisoning and treatment of carbon monoxide poisoning. Cyanide poisoning and treatment of cyanide poisoning.,13.. Pharmacogenetics, toxicogenomics, the difference between pharmacogenetics and allergic reactions.,14. Adverse drug reactions and pharmacovigilance practices in Turkey.
Dersin Öğrenme KazanımlarıTeaching MethodsAssessment Methods
1. Defines toxicology and the concept of dose.13, 16, 9A
1.1. Evaluates the ways poisons enter the body and their absorption.13, 16, 9A
1.2. Evaluates the distribution of poisons, their accumulation in the body, biotransformation and factors affecting biotransformation, and excretion of poisons.13, 16, 9A
2. Explain toxicodynamics and toxicokinetics.16, 9A
2.1. Explains systemic toxicology.16, 9A
3. Compares and evaluates poisons of plant and animal origin and their toxic effects. 13, 16, 9A
3.1. Evaluate mycotoxins and their toxic effects. 13, 16, 9A
3.2. Comments on mushroom poisoning and its treatments.13, 16, 9A
3.3. Explains pesticides and their toxic effects and treatment steps.13, 16, 9A
4. Classifies the symptoms and treatment methods of poisoning by xenobiotics.16, 9A
4.1. Evaluates acute and chronic toxicity symptoms of metals.16, 9A
4.2. Evaluate the toxic effects of organic solvents. 16, 9A
4.3. Evaluates the treatment method in cases of drug poisoning according to the symptoms and degree of poisoning.16, 9A
5. Explains first aid steps and antidotes in acute poisoning.13, 16, 9A
6. Defines the concepts of pharmacogenetics, toxicogenomics and pharmacogenetics. 13, 16, 9A
6.1. Defines the concepts of adverse effects and pharmacovigilance.13, 16, 9A
Teaching Methods:13: Case Study Method, 16: Question - Answer Technique, 9: Lecture Method
Assessment Methods:A: Traditional Written Exam

Course Outline

OrderSubjectsPreliminary Work
11.Introduction to toxicology, dose, entry ways into the body and absorption of poisons.1
22. Distribution, accumulation, biotransformation of toxicants and factors affecting biotransformation. Excretion of poisons.1
33. Toxic effect mechanisms (Toxicodynamics)1
44. Systemic toxicology. Toxicological analysis of xenobiotics. Assessment and risk analysis of the test results. Factors affecting toxicity.1,2
55. Toxic effects of organic solvents. Biomarkers.1
66. Toxic effects from herbal and animal poisons1
77. Mycotoxins and toxic effects of mycotoxins. Mushroom poisoning and treatment of mushroom poisoning1
88. First aid in acute poisoning, antidotes and treatment principles1,2
99. Toxicity of pesticides, and treatment of pesticides poisoning1
1010. Drug toxicity. Treatment of acute poisoning with drugs1
1111. Toxicity of metals.1
1212. Carbon monoxide poisoning and treatment of carbon monoxide poisoning. Cyanide poisoning and treatment of cyanide poisoning.1
1313.. Pharmacogenetics, toxicogenomics, the difference between pharmacogenetics and allergic reactions.1
1414. Adverse drug reactions and pharmacovigilance practices in Turkey1
Resources
1. The course note. 2. Nevin VURAL -TOKSİKOLOJİ, Ankara Üniversitesi Yayınları, Ankara.1996. (e-book)

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
NoProgram QualificationContribution Level
12345
1
PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences.
X
2
PQ-2. Have advanced knowledge in APIs and DPs.
3
PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field.
4
PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient.
5
PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems.
6
PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences.
7
PQ-7. Provide solutions to the professional issues using scientific knowledge and data.
8
PQ-8. Perform identification, quality control and standardization of the drug products.
9
PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments.
10
PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations.
X
11
PQ-11. Clearly show signs of adoption of life-long learning and openness to further development.
X
12
PQ-12. Critically evaluate their knowledge in pharmaceutical sciences.
X
13
PQ-13. Closely follow and evaluate the national and international professional developments.
X
14
PQ-14. Record and document all professional activities and applications.
X
15
PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public.
X
16
PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences.
17
PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products.
18
PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs.
19
PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship.
20
PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards.
21
PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues.
X

Assessment Methods

Contribution LevelAbsolute Evaluation
Rate of Midterm Exam to Success 40
Rate of Final Exam to Success 60
Total 100

Numerical Data

Ekleme Tarihi: 27/03/2023 - 11:43Son Güncelleme Tarihi: 27/03/2023 - 12:00