It is aimed to strengthen the basic biochemistry knowledge of 2 nd year students in this course, which is going to be taken in Spring. We will start the course by focusing on the structure and properties of water which is one of the important molecules that form organisms. The acid/base character of amino acids along with the structure, function, and purification methods of proteins will also be studied. This will be followed by considering the structure and function of enzyme as well as their regulation. Subsequently, the mechanism of a enzyme-ligand complex will be focused on the basis of allostery and cooperatively phenomena. Finally, some selected hot topics in the field of biochemistry will be discussed interactively with the students.
Course Content
This course contains; Molecular Interactions in a Biological Context Introduction to Biochemistry,Overview of Energy and Metabolism,Carbohydrates,Glycogen Metabolism,Glycolysis,Citric Acid Cycle,Electron Transfer Chain and Oxidative Phosphorylation,Enzyme Reactions,Lipids,Lipid Metabolism,Amino Acids,Protein Structure,Fibrous Proteins,Globular Proteins.
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
Analyzes current problems related to biochemistry
14, 16, 17, 9
A
Recognizes the basic concepts of biochemistry and biochemistry-based problems
14, 16, 17, 9
A
Recognizes basic biological molecules such as proteins, carbohydrates and lipids
14, 16, 17, 9
A
Aminoasitlerin asit/baz özellikleri tanır
14, 16, 17, 9
A
Predicts the ionization state of amino acids under different conditions.
14, 16, 17, 9
A
Tests basic biochemistry concepts
12, 14, 16, 17, 9
A
Predicts the role of enzymes in the reaction using knowledge of enzyme structure, function and regulation.
14, 16, 17, 9
A
Analyzes the factors that play a role in the formation of the Enzyme-Ligand complex
14, 16, 17, 9
A
Assess the causes of relevant diseases by having knowledge about protein, lipid and carbohydrate metabolism,
14, 16, 17, 9
A
Reports the analyzed experimental results
14, 16, 17, 9
A
Uses computer technologies to analyze results
14, 16, 17, 9
A
Teaching Methods:
12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 9: Lecture Method
Assessment Methods:
A: Traditional Written Exam
Course Outline
Order
Subjects
Preliminary Work
1
Molecular Interactions in a Biological Context Introduction to Biochemistry
Going through course materials
2
Overview of Energy and Metabolism
Going through course materials
3
Carbohydrates
Going through course materials
4
Glycogen Metabolism
Going through course materials
5
Glycolysis
Going through course materials
6
Citric Acid Cycle
Going through course materials
7
Electron Transfer Chain and Oxidative Phosphorylation
Going through course materials
8
Enzyme Reactions
Going through course materials
9
Lipids
Going through course materials
10
Lipid Metabolism
Going through course materials
11
Amino Acids
Going through course materials
12
Protein Structure
Going through course materials
13
Fibrous Proteins
Going through course materials
14
Globular Proteins
Going through course materials
Resources
Principles of Biochemistry - 5 th edition - Laurence A. Moran & Robert A. Horton 2. Biochemistry - 8 th edition- Mary K. Campbell & Shawn O. Farrell.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
An ability to apply knowledge of mathematics, science, and engineering
X
2
An ability to identify, formulate, and solve engineering problems
X
3
An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
4
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
5
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
6
An ability to function on multidisciplinary teams
X
7
An ability to communicate effectively
X
8
A recognition of the need for, and an ability to engage in life-long learning
X
9
An understanding of professional and ethical responsibility
10
A knowledge of contemporary issues
11
The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
12
Capability to apply and decide on engineering principals while understanding and rehabilitating the human body
X
Assessment Methods
Contribution Level
Absolute Evaluation
Rate of Midterm Exam to Success
30
Rate of Final Exam to Success
70
Total
100
ECTS / Workload Table
Activities
Number of
Duration(Hour)
Total Workload(Hour)
Course Hours
14
4
56
Guided Problem Solving
14
4
56
Resolution of Homework Problems and Submission as a Report
4
5
20
Term Project
0
0
0
Presentation of Project / Seminar
0
0
0
Quiz
0
0
0
Midterm Exam
1
20
20
General Exam
1
30
30
Performance Task, Maintenance Plan
0
0
0
Total Workload(Hour)
182
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(182/30)
6
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.
Detail Informations of the Course
Course Description
Course
Code
Semester
T+P (Hour)
Credit
ECTS
BIOCHEMISTRY
BME2221320
Spring Semester
3+2
4
6
Course Program
Pazartesi 12:00-12:45
Pazartesi 12:45-13:30
Pazartesi 13:30-14:15
Pazartesi 14:30-15:15
Pazartesi 17:30-18:15
Pazartesi 18:30-19:15
Pazartesi 19:30-20:15
Prerequisites Courses
Recommended Elective Courses
Language of Course
English
Course Level
First Cycle (Bachelor's Degree)
Course Type
Required
Course Coordinator
Assoc.Prof. Sultan Sibel ERDEM
Name of Lecturer(s)
Assist.Prof. Nihan VERİMLİ
Assistant(s)
Aim
It is aimed to strengthen the basic biochemistry knowledge of 2 nd year students in this course, which is going to be taken in Spring. We will start the course by focusing on the structure and properties of water which is one of the important molecules that form organisms. The acid/base character of amino acids along with the structure, function, and purification methods of proteins will also be studied. This will be followed by considering the structure and function of enzyme as well as their regulation. Subsequently, the mechanism of a enzyme-ligand complex will be focused on the basis of allostery and cooperatively phenomena. Finally, some selected hot topics in the field of biochemistry will be discussed interactively with the students.
Course Content
This course contains; Molecular Interactions in a Biological Context Introduction to Biochemistry,Overview of Energy and Metabolism,Carbohydrates,Glycogen Metabolism,Glycolysis,Citric Acid Cycle,Electron Transfer Chain and Oxidative Phosphorylation,Enzyme Reactions,Lipids,Lipid Metabolism,Amino Acids,Protein Structure,Fibrous Proteins,Globular Proteins.
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
Analyzes current problems related to biochemistry
14, 16, 17, 9
A
Recognizes the basic concepts of biochemistry and biochemistry-based problems
14, 16, 17, 9
A
Recognizes basic biological molecules such as proteins, carbohydrates and lipids
14, 16, 17, 9
A
Aminoasitlerin asit/baz özellikleri tanır
14, 16, 17, 9
A
Predicts the ionization state of amino acids under different conditions.
14, 16, 17, 9
A
Tests basic biochemistry concepts
12, 14, 16, 17, 9
A
Predicts the role of enzymes in the reaction using knowledge of enzyme structure, function and regulation.
14, 16, 17, 9
A
Analyzes the factors that play a role in the formation of the Enzyme-Ligand complex
14, 16, 17, 9
A
Assess the causes of relevant diseases by having knowledge about protein, lipid and carbohydrate metabolism,
14, 16, 17, 9
A
Reports the analyzed experimental results
14, 16, 17, 9
A
Uses computer technologies to analyze results
14, 16, 17, 9
A
Teaching Methods:
12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 9: Lecture Method
Assessment Methods:
A: Traditional Written Exam
Course Outline
Order
Subjects
Preliminary Work
1
Molecular Interactions in a Biological Context Introduction to Biochemistry
Going through course materials
2
Overview of Energy and Metabolism
Going through course materials
3
Carbohydrates
Going through course materials
4
Glycogen Metabolism
Going through course materials
5
Glycolysis
Going through course materials
6
Citric Acid Cycle
Going through course materials
7
Electron Transfer Chain and Oxidative Phosphorylation
Going through course materials
8
Enzyme Reactions
Going through course materials
9
Lipids
Going through course materials
10
Lipid Metabolism
Going through course materials
11
Amino Acids
Going through course materials
12
Protein Structure
Going through course materials
13
Fibrous Proteins
Going through course materials
14
Globular Proteins
Going through course materials
Resources
Principles of Biochemistry - 5 th edition - Laurence A. Moran & Robert A. Horton 2. Biochemistry - 8 th edition- Mary K. Campbell & Shawn O. Farrell.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
An ability to apply knowledge of mathematics, science, and engineering
X
2
An ability to identify, formulate, and solve engineering problems
X
3
An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
4
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
5
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
6
An ability to function on multidisciplinary teams
X
7
An ability to communicate effectively
X
8
A recognition of the need for, and an ability to engage in life-long learning
X
9
An understanding of professional and ethical responsibility
10
A knowledge of contemporary issues
11
The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
12
Capability to apply and decide on engineering principals while understanding and rehabilitating the human body
