Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY & GENETICS | - | Yearly | 66+0 | - | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Assist.Prof. Neşe AYŞİT |
| Name of Lecturer(s) | Assist.Prof. İlyas ÖZÇİÇEK, Assist.Prof. Elif Zeynep YILMAZ, Assist.Prof. Neşe AYŞİT, Prof.Dr. Kürşat ÖZDİLLİ, Assoc.Prof. Nihal KARAKAŞ |
| Assistant(s) | |
| Aim | The aim of this course is to define the fundamental concepts in cellular, molecular and functional aspects of medical biology and genetics of the cell, to evaluate association of pathologies and homeostasis with molecular mechanisms that will lay the foundation for understanding of basic cellular mechanisms for clinical applications that meets the requirements for dentistry proficiency and learning objectives. |
| Course Content | This course contains; Fundamentals of Life: Cell,Cell Biology Basic Chemical Concepts and Biosynthesis, Basic Structure and Functions of Proteins, Genetic Material of the Cell: DNA, Chromosomes and Genome,DNA Replication and Repair,RNA Structure and Transcription,Genetic Code and Translation,Control Mechanisms of Gene Expression and Cellular Genetic Switches-I,Control Mechanisms of Gene Expression and Cellular Genetic Switches-II,Epigenetics and Epigenome,Molecular Techniques and Clinical Applications,Structure and Function of Cellular Membranes and Transport of Small Molecules in the Cell Membrane,Intracellular Compartments: Organelles-I,Intracellular Compartments: Organelles-II,Intracellular Compartments: Organelles-III,Intracellular Protein Transport and Interorganellar Vesicle Traffic,Endocytosis, Exocytosis and Membrane Transport,Cellular Communication and Signal Pathways –I,Cellular Communication and Signal Pathways –II,Cytoskeleton and Motor Proteins,Intercellular Connections, Cell Adhesion and Extracellular Matrix,Cell Cycle, Cell Aging and Death,Developmental Biology and Organ Regeneration,Fundamentals and Clinical Applications of Stem Cell,Cancer Biology and Molecular Basis of Cancer,Current Treatment Approaches to Cancer,Basic Concepts in Medical Genetics,Mendelian genetics,Non-Mendelian genetics,Autosomal Chromosome diseases,Sex chromosome-related genetic diseases,Prenatal Testing and Genetic Counseling. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Defines structural, functional, normal and pathological conditions at the human cell level with their basic mechanisms. | 14 | C |
| Classifies diseases at the cellular, molecular and genetic levels. | 14 | C |
| Explains medical biology information at an advanced level in dentistry practices. | 14 | C |
| Explains basic biological mechanisms from molecules to cells, from cells to tissues and organs. | 14 | C |
| Describes genetic problems frequently encountered in society. | 14 | C |
| Associates and interprets the homeostasis and disease-related information obtained in medical biological sciences with the field of dentistry. | 14 | C |
| Teaching Methods: | 14: Self Study Method |
| Assessment Methods: | C: Multiple-Choice Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Fundamentals of Life: Cell | |
| 2 | Cell Biology Basic Chemical Concepts and Biosynthesis | |
| 3 | Basic Structure and Functions of Proteins | |
| 4 | Genetic Material of the Cell: DNA, Chromosomes and Genome | |
| 5 | DNA Replication and Repair | |
| 6 | RNA Structure and Transcription | |
| 7 | Genetic Code and Translation | |
| 8 | Control Mechanisms of Gene Expression and Cellular Genetic Switches-I | |
| 9 | Control Mechanisms of Gene Expression and Cellular Genetic Switches-II | |
| 10 | Epigenetics and Epigenome | |
| 11 | Molecular Techniques and Clinical Applications | |
| 12 | Structure and Function of Cellular Membranes and Transport of Small Molecules in the Cell Membrane | |
| 13 | Intracellular Compartments: Organelles-I | |
| 14 | Intracellular Compartments: Organelles-II | |
| 15 | Intracellular Compartments: Organelles-III | |
| 16 | Intracellular Protein Transport and Interorganellar Vesicle Traffic | |
| 17 | Endocytosis, Exocytosis and Membrane Transport | |
| 18 | Cellular Communication and Signal Pathways –I | |
| 19 | Cellular Communication and Signal Pathways –II | |
| 20 | Cytoskeleton and Motor Proteins | |
| 21 | Intercellular Connections, Cell Adhesion and Extracellular Matrix | |
| 22 | Cell Cycle | |
| 23 | Cell Aging and Death | |
| 24 | Developmental Biology and Organ Regeneration | |
| 25 | Fundamentals and Clinical Applications of Stem Cell | |
| 26 | Cancer Biology and Molecular Basis of Cancer | |
| 27 | Current Treatment Approaches to Cancer | |
| 28 | Basic Concepts in Medical Genetics | |
| 29 | Mendelian genetics | |
| 30 | Non-Mendelian genetics | |
| 31 | Autosomal Chromosome diseases | |
| 32 | Sex chromosome-related genetic diseases | |
| 33 | Prenatal Testing and Genetic Counseling |
| Resources |
| Course books, lecture notes and slides. 1. Essential Cell Biology, Fifth Edition, Alberts et al, Garland Science Publishing, 2019 2. Molecular Biology of the Cell, Sixth Edition; Alberts et al, Garland Science Publishing, 2017 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. He/She has the ability to monitor and evaluate the practical tools used in the field of dentistry, the literature containing the most up-to-date information and other resources. | X | |||||
| 2 | PQ-2. He/She has the knowledge to evaluate the source, accuracy, reliability and validity of the information obtained in the field of dentistry. He/she integrates this information with the information of all disciplines in the field of health, analyzes it and uses it in his/her professional practices. | X | |||||
| 3 | PQ-3. He/She interprets and evaluates scientifically proven data, identifies and analyzes problems, develops solution suggestions and provides the most ideal treatment for patients by using the advanced theoretical and practical knowledge acquired in the field of dentistry. | X | |||||
| 4 | PQ-4. He/She provides health education for individuals, families and society by integrating its knowledge in the field of dentistry with the knowledge of other health disciplines, creating interpretations and new information. | X | |||||
| 5 | PQ-5. He/She clearly conveys her thoughts, problems and solution methods, and produces solutions to problems in line with scientific data and evidence by using the advanced theoretical and practical knowledge he/she has acquired in the field of dentistry. | X | |||||
| 6 | PQ-6. He/She independently carries out a study related to the field of dentistry using her advanced knowledge | ||||||
| 7 | PQ-7. He/She takes responsibility as a team member or individually to solve complex and unpredictable problems encountered in dental applications. | ||||||
| 8 | PQ-8. He/She assumes the leadership role in solving problems in the field of dentistry, plans and manages activities for the development of employees under its responsibility and examines and evaluates the process. | X | |||||
| 9 | PQ-9 He/She determines the learning needs and goals in the field of dentistry and directs its learning by accessing resources effectively and quickly. He/She is open to development, develops a positive attitude towards lifelong learning and continues this behavior throughout her professional life. | X | |||||
| 10 | PQ-10. He/She informs relevant people and institutions on issues related to the field of dentistry, listens to their thoughts, wishes and expectations, and conveys his/her own thoughts and solution suggestions to problems to experts and non-experts by supporting them with quantitative and qualitative data. | ||||||
| 11 | PQ-11. He/she examines and improves his/her knowledge in the field of dentistry with his/her colleagues, patients and relatives, with a critical perspective specific to each individual. | ||||||
| 12 | PQ-12. He/She knows a foreign language (English) at a level that allows him/her to continue his/her professional development by following international publications and meetings in the field of dentistry and to communicate verbally and in writing with his/her colleagues. | X | |||||
| 13 | PQ-13. He/She uses information and communication technologies along with knowledge of computer software and hardware at the level required by the field of dentistry. | X | |||||
| 14 | PQ-14. While practicing dentistry, he/she respects social, scientific, cultural and ethical values in the collection, interpretation, application and announcement of patient data and teaches these values. | ||||||
| 15 | PQ-15.He/She develops and implements strategies, policies and implementation plans on matters related to dentistry and evaluates the results within the framework of quality processes. | X | |||||
| 16 | PQ-16. He/She uses the knowledge she has absorbed in the field of dentistry in interdisciplinary studies to solve oral and dental health problems of the individual and community. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 33 | 2 | 66 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 5 | 10 | 50 | |||
| General Exam | 1 | 20 | 20 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 136 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(136/30) | 5 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY & GENETICS | - | Yearly | 66+0 | - | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Assist.Prof. Neşe AYŞİT |
| Name of Lecturer(s) | Assist.Prof. İlyas ÖZÇİÇEK, Assist.Prof. Elif Zeynep YILMAZ, Assist.Prof. Neşe AYŞİT, Prof.Dr. Kürşat ÖZDİLLİ, Assoc.Prof. Nihal KARAKAŞ |
| Assistant(s) | |
| Aim | The aim of this course is to define the fundamental concepts in cellular, molecular and functional aspects of medical biology and genetics of the cell, to evaluate association of pathologies and homeostasis with molecular mechanisms that will lay the foundation for understanding of basic cellular mechanisms for clinical applications that meets the requirements for dentistry proficiency and learning objectives. |
| Course Content | This course contains; Fundamentals of Life: Cell,Cell Biology Basic Chemical Concepts and Biosynthesis, Basic Structure and Functions of Proteins, Genetic Material of the Cell: DNA, Chromosomes and Genome,DNA Replication and Repair,RNA Structure and Transcription,Genetic Code and Translation,Control Mechanisms of Gene Expression and Cellular Genetic Switches-I,Control Mechanisms of Gene Expression and Cellular Genetic Switches-II,Epigenetics and Epigenome,Molecular Techniques and Clinical Applications,Structure and Function of Cellular Membranes and Transport of Small Molecules in the Cell Membrane,Intracellular Compartments: Organelles-I,Intracellular Compartments: Organelles-II,Intracellular Compartments: Organelles-III,Intracellular Protein Transport and Interorganellar Vesicle Traffic,Endocytosis, Exocytosis and Membrane Transport,Cellular Communication and Signal Pathways –I,Cellular Communication and Signal Pathways –II,Cytoskeleton and Motor Proteins,Intercellular Connections, Cell Adhesion and Extracellular Matrix,Cell Cycle, Cell Aging and Death,Developmental Biology and Organ Regeneration,Fundamentals and Clinical Applications of Stem Cell,Cancer Biology and Molecular Basis of Cancer,Current Treatment Approaches to Cancer,Basic Concepts in Medical Genetics,Mendelian genetics,Non-Mendelian genetics,Autosomal Chromosome diseases,Sex chromosome-related genetic diseases,Prenatal Testing and Genetic Counseling. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Defines structural, functional, normal and pathological conditions at the human cell level with their basic mechanisms. | 14 | C |
| Classifies diseases at the cellular, molecular and genetic levels. | 14 | C |
| Explains medical biology information at an advanced level in dentistry practices. | 14 | C |
| Explains basic biological mechanisms from molecules to cells, from cells to tissues and organs. | 14 | C |
| Describes genetic problems frequently encountered in society. | 14 | C |
| Associates and interprets the homeostasis and disease-related information obtained in medical biological sciences with the field of dentistry. | 14 | C |
| Teaching Methods: | 14: Self Study Method |
| Assessment Methods: | C: Multiple-Choice Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Fundamentals of Life: Cell | |
| 2 | Cell Biology Basic Chemical Concepts and Biosynthesis | |
| 3 | Basic Structure and Functions of Proteins | |
| 4 | Genetic Material of the Cell: DNA, Chromosomes and Genome | |
| 5 | DNA Replication and Repair | |
| 6 | RNA Structure and Transcription | |
| 7 | Genetic Code and Translation | |
| 8 | Control Mechanisms of Gene Expression and Cellular Genetic Switches-I | |
| 9 | Control Mechanisms of Gene Expression and Cellular Genetic Switches-II | |
| 10 | Epigenetics and Epigenome | |
| 11 | Molecular Techniques and Clinical Applications | |
| 12 | Structure and Function of Cellular Membranes and Transport of Small Molecules in the Cell Membrane | |
| 13 | Intracellular Compartments: Organelles-I | |
| 14 | Intracellular Compartments: Organelles-II | |
| 15 | Intracellular Compartments: Organelles-III | |
| 16 | Intracellular Protein Transport and Interorganellar Vesicle Traffic | |
| 17 | Endocytosis, Exocytosis and Membrane Transport | |
| 18 | Cellular Communication and Signal Pathways –I | |
| 19 | Cellular Communication and Signal Pathways –II | |
| 20 | Cytoskeleton and Motor Proteins | |
| 21 | Intercellular Connections, Cell Adhesion and Extracellular Matrix | |
| 22 | Cell Cycle | |
| 23 | Cell Aging and Death | |
| 24 | Developmental Biology and Organ Regeneration | |
| 25 | Fundamentals and Clinical Applications of Stem Cell | |
| 26 | Cancer Biology and Molecular Basis of Cancer | |
| 27 | Current Treatment Approaches to Cancer | |
| 28 | Basic Concepts in Medical Genetics | |
| 29 | Mendelian genetics | |
| 30 | Non-Mendelian genetics | |
| 31 | Autosomal Chromosome diseases | |
| 32 | Sex chromosome-related genetic diseases | |
| 33 | Prenatal Testing and Genetic Counseling |
| Resources |
| Course books, lecture notes and slides. 1. Essential Cell Biology, Fifth Edition, Alberts et al, Garland Science Publishing, 2019 2. Molecular Biology of the Cell, Sixth Edition; Alberts et al, Garland Science Publishing, 2017 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. He/She has the ability to monitor and evaluate the practical tools used in the field of dentistry, the literature containing the most up-to-date information and other resources. | X | |||||
| 2 | PQ-2. He/She has the knowledge to evaluate the source, accuracy, reliability and validity of the information obtained in the field of dentistry. He/she integrates this information with the information of all disciplines in the field of health, analyzes it and uses it in his/her professional practices. | X | |||||
| 3 | PQ-3. He/She interprets and evaluates scientifically proven data, identifies and analyzes problems, develops solution suggestions and provides the most ideal treatment for patients by using the advanced theoretical and practical knowledge acquired in the field of dentistry. | X | |||||
| 4 | PQ-4. He/She provides health education for individuals, families and society by integrating its knowledge in the field of dentistry with the knowledge of other health disciplines, creating interpretations and new information. | X | |||||
| 5 | PQ-5. He/She clearly conveys her thoughts, problems and solution methods, and produces solutions to problems in line with scientific data and evidence by using the advanced theoretical and practical knowledge he/she has acquired in the field of dentistry. | X | |||||
| 6 | PQ-6. He/She independently carries out a study related to the field of dentistry using her advanced knowledge | ||||||
| 7 | PQ-7. He/She takes responsibility as a team member or individually to solve complex and unpredictable problems encountered in dental applications. | ||||||
| 8 | PQ-8. He/She assumes the leadership role in solving problems in the field of dentistry, plans and manages activities for the development of employees under its responsibility and examines and evaluates the process. | X | |||||
| 9 | PQ-9 He/She determines the learning needs and goals in the field of dentistry and directs its learning by accessing resources effectively and quickly. He/She is open to development, develops a positive attitude towards lifelong learning and continues this behavior throughout her professional life. | X | |||||
| 10 | PQ-10. He/She informs relevant people and institutions on issues related to the field of dentistry, listens to their thoughts, wishes and expectations, and conveys his/her own thoughts and solution suggestions to problems to experts and non-experts by supporting them with quantitative and qualitative data. | ||||||
| 11 | PQ-11. He/she examines and improves his/her knowledge in the field of dentistry with his/her colleagues, patients and relatives, with a critical perspective specific to each individual. | ||||||
| 12 | PQ-12. He/She knows a foreign language (English) at a level that allows him/her to continue his/her professional development by following international publications and meetings in the field of dentistry and to communicate verbally and in writing with his/her colleagues. | X | |||||
| 13 | PQ-13. He/She uses information and communication technologies along with knowledge of computer software and hardware at the level required by the field of dentistry. | X | |||||
| 14 | PQ-14. While practicing dentistry, he/she respects social, scientific, cultural and ethical values in the collection, interpretation, application and announcement of patient data and teaches these values. | ||||||
| 15 | PQ-15.He/She develops and implements strategies, policies and implementation plans on matters related to dentistry and evaluates the results within the framework of quality processes. | X | |||||
| 16 | PQ-16. He/She uses the knowledge she has absorbed in the field of dentistry in interdisciplinary studies to solve oral and dental health problems of the individual and community. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |