Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY & GENETICS | - | Yearly | 44+10 | - | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Prof.Dr. Esra ÇAĞAVİ |
| Name of Lecturer(s) | Assist.Prof. İlyas ÖZÇİÇEK, Prof.Dr. Esra ÇAĞAVİ, Assoc.Prof. Nihal KARAKAŞ, Assist.Prof. Neşe AYŞİT, Prof.Dr. Kürşat ÖZDİLLİ |
| Assistant(s) | None |
| Aim | The aim of this course is to define and evaluate the fundamental concepts in medical biology and medical genetics, that will lay the foundation for first year medical students for understanding of basic cellular mechanisms as well as associating the dysfunctional molecular mechanisms with human diseases. |
| Course Content | This course contains; Fundamentals of life - the cell,Chemical principles of the cell biology and biosynthesis,Protein structure and function,Genetic material of the cell - DNA, chromosomes and the genome,DNA replication and repair,RNA structure and transcription,Genetic code and tranlation,Control of gene expression and genetic switches-I,Control of gene expression and genetic switches-II,Epigenetics and epigenome,Molecular techniques and clinical applications,The structure and function of cellular membranes and transport across the membrane,Cellular compartments: Organelles-I,Cellular compartments: Organelles-II,Cellular compartments: Organelles-III,Vesicular transport within the cell,Endocytosis, exocytosis and membrane transport,Cell Signaling -I,Cell Signaling -II,Cytoskeleton and motor proteins,Cell adhesion, junctions and extracellular matrix,Cell cycle,Cell senescence and cell death,Developmental biology and organ regeneration,Stem cells and regenerative medicine,Cancer biology and molecular basis of cancer,Current therapeutic approaches and cancer therapy,Fundamentals of medical genetics,Mendelian/non-mendelian/population genetics,Principles of autosomal genetic inheritance,Principles of genetic inheritance sex chromosomes,Gonosomal and autosomal chromosomal abnormalities,Prenatal testing and genetic counseling. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 10, 12, 14, 16, 17, 19, 3, 37, 4, 9 | A, E, G |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 3: Problem Baded Learning Model, 37: Computer-Internet Supported Instruction, 4: Inquiry-Based Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework, G: Quiz |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Fundamentals of life - the cell | |
| 2 | Chemical principles of the cell biology and biosynthesis | |
| 3 | Protein structure and function | |
| 4 | Genetic material of the cell - DNA, chromosomes and the genome | |
| 5 | DNA replication and repair | |
| 6 | RNA structure and transcription | |
| 7 | Genetic code and tranlation | |
| 8 | Control of gene expression and genetic switches-I | |
| 9 | Control of gene expression and genetic switches-II | |
| 10 | Epigenetics and epigenome | |
| 11 | Molecular techniques and clinical applications | |
| 12 | The structure and function of cellular membranes and transport across the membrane | |
| 13 | Cellular compartments: Organelles-I | |
| 14 | Cellular compartments: Organelles-II | |
| 15 | Cellular compartments: Organelles-III | |
| 16 | Vesicular transport within the cell | |
| 17 | Endocytosis, exocytosis and membrane transport | |
| 18 | Cell Signaling -I | |
| 19 | Cell Signaling -II | |
| 20 | Cytoskeleton and motor proteins | |
| 21 | Cell adhesion, junctions and extracellular matrix | |
| 22 | Cell cycle | |
| 23 | Cell senescence and cell death | |
| 24 | Developmental biology and organ regeneration | |
| 25 | Stem cells and regenerative medicine | |
| 26 | Cancer biology and molecular basis of cancer | |
| 27 | Current therapeutic approaches and cancer therapy | |
| 28 | Fundamentals of medical genetics | |
| 29 | Mendelian/non-mendelian/population genetics | |
| 30 | Principles of autosomal genetic inheritance | |
| 31 | Principles of genetic inheritance sex chromosomes | |
| 32 | Gonosomal and autosomal chromosomal abnormalities | |
| 33 | Prenatal testing and genetic counseling |
| Resources |
| Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter “Essential Cell Biology” Fourth Edition, Garland Science Publishers, USA, 2013. |
| 1. Presentations of lecture notes 2. Stephen R Goodman “Medical Cell Biology”, Third Edition, Elsevier, USA, 2007. 3. Alberts, Johnson, Lewis, Raff, Roberts, Walter “Molecular Biology of the Cell” Sixth Edition, Garland Science Publishers, USA, 2013. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | ||||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | ||||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | ||||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | ||||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | ||||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | ||||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | ||||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | ||||||
| 9 | Plans and conducts an advanced study on health independently. | ||||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | ||||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | ||||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | ||||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | ||||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | ||||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | ||||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | ||||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | ||||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | ||||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | ||||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | ||||||
| 21 | Has adequate awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 0 | 0 | 0 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 0 | 0 | 0 | |||
| General Exam | 0 | 0 | 0 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 0 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(0/30) | 0 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY & GENETICS | - | Yearly | 44+10 | - | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Prof.Dr. Esra ÇAĞAVİ |
| Name of Lecturer(s) | Assist.Prof. İlyas ÖZÇİÇEK, Prof.Dr. Esra ÇAĞAVİ, Assoc.Prof. Nihal KARAKAŞ, Assist.Prof. Neşe AYŞİT, Prof.Dr. Kürşat ÖZDİLLİ |
| Assistant(s) | None |
| Aim | The aim of this course is to define and evaluate the fundamental concepts in medical biology and medical genetics, that will lay the foundation for first year medical students for understanding of basic cellular mechanisms as well as associating the dysfunctional molecular mechanisms with human diseases. |
| Course Content | This course contains; Fundamentals of life - the cell,Chemical principles of the cell biology and biosynthesis,Protein structure and function,Genetic material of the cell - DNA, chromosomes and the genome,DNA replication and repair,RNA structure and transcription,Genetic code and tranlation,Control of gene expression and genetic switches-I,Control of gene expression and genetic switches-II,Epigenetics and epigenome,Molecular techniques and clinical applications,The structure and function of cellular membranes and transport across the membrane,Cellular compartments: Organelles-I,Cellular compartments: Organelles-II,Cellular compartments: Organelles-III,Vesicular transport within the cell,Endocytosis, exocytosis and membrane transport,Cell Signaling -I,Cell Signaling -II,Cytoskeleton and motor proteins,Cell adhesion, junctions and extracellular matrix,Cell cycle,Cell senescence and cell death,Developmental biology and organ regeneration,Stem cells and regenerative medicine,Cancer biology and molecular basis of cancer,Current therapeutic approaches and cancer therapy,Fundamentals of medical genetics,Mendelian/non-mendelian/population genetics,Principles of autosomal genetic inheritance,Principles of genetic inheritance sex chromosomes,Gonosomal and autosomal chromosomal abnormalities,Prenatal testing and genetic counseling. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 10, 12, 14, 16, 17, 19, 3, 37, 4, 9 | A, E, G |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 3: Problem Baded Learning Model, 37: Computer-Internet Supported Instruction, 4: Inquiry-Based Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework, G: Quiz |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Fundamentals of life - the cell | |
| 2 | Chemical principles of the cell biology and biosynthesis | |
| 3 | Protein structure and function | |
| 4 | Genetic material of the cell - DNA, chromosomes and the genome | |
| 5 | DNA replication and repair | |
| 6 | RNA structure and transcription | |
| 7 | Genetic code and tranlation | |
| 8 | Control of gene expression and genetic switches-I | |
| 9 | Control of gene expression and genetic switches-II | |
| 10 | Epigenetics and epigenome | |
| 11 | Molecular techniques and clinical applications | |
| 12 | The structure and function of cellular membranes and transport across the membrane | |
| 13 | Cellular compartments: Organelles-I | |
| 14 | Cellular compartments: Organelles-II | |
| 15 | Cellular compartments: Organelles-III | |
| 16 | Vesicular transport within the cell | |
| 17 | Endocytosis, exocytosis and membrane transport | |
| 18 | Cell Signaling -I | |
| 19 | Cell Signaling -II | |
| 20 | Cytoskeleton and motor proteins | |
| 21 | Cell adhesion, junctions and extracellular matrix | |
| 22 | Cell cycle | |
| 23 | Cell senescence and cell death | |
| 24 | Developmental biology and organ regeneration | |
| 25 | Stem cells and regenerative medicine | |
| 26 | Cancer biology and molecular basis of cancer | |
| 27 | Current therapeutic approaches and cancer therapy | |
| 28 | Fundamentals of medical genetics | |
| 29 | Mendelian/non-mendelian/population genetics | |
| 30 | Principles of autosomal genetic inheritance | |
| 31 | Principles of genetic inheritance sex chromosomes | |
| 32 | Gonosomal and autosomal chromosomal abnormalities | |
| 33 | Prenatal testing and genetic counseling |
| Resources |
| Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter “Essential Cell Biology” Fourth Edition, Garland Science Publishers, USA, 2013. |
| 1. Presentations of lecture notes 2. Stephen R Goodman “Medical Cell Biology”, Third Edition, Elsevier, USA, 2007. 3. Alberts, Johnson, Lewis, Raff, Roberts, Walter “Molecular Biology of the Cell” Sixth Edition, Garland Science Publishers, USA, 2013. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | ||||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | ||||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | ||||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | ||||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | ||||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | ||||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | ||||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | ||||||
| 9 | Plans and conducts an advanced study on health independently. | ||||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | ||||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | ||||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | ||||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | ||||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | ||||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | ||||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | ||||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | ||||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | ||||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | ||||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | ||||||
| 21 | Has adequate awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |