Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL CHEMISTRY III | - | Fall Semester | 3+0 | 3 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Seda ÜNSALAN |
| Name of Lecturer(s) | |
| Assistant(s) | |
| Aim | The aim of this course is to inform about drugs effected on otonom nervous system and cardiovascular system and otacoids, hormons and their related drugs. |
| Course Content | This course contains; Direct and indirect sympathomimetics and sympatholytics.,Direct and indirect parasympathomimetics and parasympatholytics.,Drugs used in heart failure, antiarrhythmics and antiallergens.,Calcium channel blockers, peripheric vasodilators and adrenergic receptor blockers.,Hemostatics, anticoagulants, antithrombolytics and antianemics.,Arterial and venous vasodilators, drugs acting on vascular smooth muscle and direckt acting vasodilators.,drugs acting on renin-angiotensin system.,Diuretics and antihyperlipidemic drugs.,Digestants, antiulcer agents, emetic and amtiemetics, laxatives and antidiarrheals.,Thyroid and peptide hormones and antidiabetics.,Sex hormones.,Adrenocorticoids., Antihistaminics,Radiocontrasts, vitamine and immunomodulators.. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1.evaluate the drugs acting on autonomous nervous system. | 16, 19, 9 | A |
| 1.1.debate the structure activity relationships of the drugs acting on sempatic system. | 16, 19, 9 | A |
| 1.2. debate the structure activity relationships of the drugs acting on parasempatic system. | 16, 19, 9 | A |
| 1.3. illustrate the synthetic methods of the drugs acting on autonomous nervous system. | 16, 19, 9 | A |
| 2. relate the drugs acting on cardiovascular system. | 16, 19, 9 | A |
| 2.1. illustrate the structure activity relationships of antiarrhythmic and antianginal drugs. | 16, 19, 9 | A |
| 2.2. debate the structure activity relationships of peripheric vasodilators and adrenergic neuron and receptor blockers. | 16, 19, 9 | A |
| 2.3. compare the effects of drugs acting on the renin-angiotensin system. | 16, 19, 9 | A |
| 2.4. Illustrate synthesis methods of drugs effective on the cardiovascular system | 16, 19, 9 | A |
| 3. distinguish direckt acting vasodilators. | 16, 19, 9 | A |
| 3.1. debate the structure activity relationships of the drugs acting on vascular smooth muscle. | 16, 19, 9 | A |
| 3.2. debate the structure activity relationships of the ganglion blokers. | 16, 19, 9 | A |
| 3.3. debate the structure activity relationships of the drugs acting on renin-angiotensin system. | 16, 19, 9 | A |
| 3.4. illustrate the synthetic methods of the vasodilator drugs. | 16, 19, 9 | A |
| 4. compare hormones and otacoids. | 16, 19, 9 | A |
| 4.1. interpret the structure activity relationships of hormone and otacoid-structured drugs. | 16, 19, 9 | A |
| 4.2. interpret the structure activity relationships of the sex hormones. | 16, 19, 9 | A |
| 4.3. interpret the structure activity relationships of the antihistaminic drugs. | 16, 19, 9 | A |
| 4.4. illustrate the synthetic methods of the hormones and otacoids | 16, 19, 9 | A |
| Teaching Methods: | 16: Question - Answer Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Direct and indirect sympathomimetics and sympatholytics. | 1 |
| 2 | Direct and indirect parasympathomimetics and parasympatholytics. | 1 |
| 3 | Drugs used in heart failure, antiarrhythmics and antiallergens. | 1 |
| 4 | Calcium channel blockers, peripheric vasodilators and adrenergic receptor blockers. | 1 |
| 5 | Hemostatics, anticoagulants, antithrombolytics and antianemics. | 1 |
| 6 | Arterial and venous vasodilators, drugs acting on vascular smooth muscle and direckt acting vasodilators. | 1 |
| 7 | drugs acting on renin-angiotensin system. | 1 |
| 8 | Diuretics and antihyperlipidemic drugs. | 1 |
| 9 | Digestants, antiulcer agents, emetic and amtiemetics, laxatives and antidiarrheals. | 1 |
| 10 | Thyroid and peptide hormones and antidiabetics. | 1 |
| 11 | Sex hormones. | 1 |
| 12 | Adrenocorticoids. | 1 |
| 13 | Antihistaminics | 1 |
| 14 | Radiocontrasts, vitamine and immunomodulators. | 1 |
| Resources |
| Pharmaceutical chemistry III notes will be given to the students. |
| 1. Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı Öğretim Üyeleri. (2004) Farmasötik Kimya. Hacettepe Üniversitesi Yayınları, Ankara. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 14 | 3 | 42 | |||
| Resolution of Homework Problems and Submission as a Report | 14 | 2 | 28 | |||
| Term Project | 5 | 2 | 10 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 7 | 2 | 14 | |||
| General Exam | 7 | 2 | 14 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 150 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(150/30) | 5 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL CHEMISTRY III | - | Fall Semester | 3+0 | 3 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Seda ÜNSALAN |
| Name of Lecturer(s) | |
| Assistant(s) | |
| Aim | The aim of this course is to inform about drugs effected on otonom nervous system and cardiovascular system and otacoids, hormons and their related drugs. |
| Course Content | This course contains; Direct and indirect sympathomimetics and sympatholytics.,Direct and indirect parasympathomimetics and parasympatholytics.,Drugs used in heart failure, antiarrhythmics and antiallergens.,Calcium channel blockers, peripheric vasodilators and adrenergic receptor blockers.,Hemostatics, anticoagulants, antithrombolytics and antianemics.,Arterial and venous vasodilators, drugs acting on vascular smooth muscle and direckt acting vasodilators.,drugs acting on renin-angiotensin system.,Diuretics and antihyperlipidemic drugs.,Digestants, antiulcer agents, emetic and amtiemetics, laxatives and antidiarrheals.,Thyroid and peptide hormones and antidiabetics.,Sex hormones.,Adrenocorticoids., Antihistaminics,Radiocontrasts, vitamine and immunomodulators.. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1.evaluate the drugs acting on autonomous nervous system. | 16, 19, 9 | A |
| 1.1.debate the structure activity relationships of the drugs acting on sempatic system. | 16, 19, 9 | A |
| 1.2. debate the structure activity relationships of the drugs acting on parasempatic system. | 16, 19, 9 | A |
| 1.3. illustrate the synthetic methods of the drugs acting on autonomous nervous system. | 16, 19, 9 | A |
| 2. relate the drugs acting on cardiovascular system. | 16, 19, 9 | A |
| 2.1. illustrate the structure activity relationships of antiarrhythmic and antianginal drugs. | 16, 19, 9 | A |
| 2.2. debate the structure activity relationships of peripheric vasodilators and adrenergic neuron and receptor blockers. | 16, 19, 9 | A |
| 2.3. compare the effects of drugs acting on the renin-angiotensin system. | 16, 19, 9 | A |
| 2.4. Illustrate synthesis methods of drugs effective on the cardiovascular system | 16, 19, 9 | A |
| 3. distinguish direckt acting vasodilators. | 16, 19, 9 | A |
| 3.1. debate the structure activity relationships of the drugs acting on vascular smooth muscle. | 16, 19, 9 | A |
| 3.2. debate the structure activity relationships of the ganglion blokers. | 16, 19, 9 | A |
| 3.3. debate the structure activity relationships of the drugs acting on renin-angiotensin system. | 16, 19, 9 | A |
| 3.4. illustrate the synthetic methods of the vasodilator drugs. | 16, 19, 9 | A |
| 4. compare hormones and otacoids. | 16, 19, 9 | A |
| 4.1. interpret the structure activity relationships of hormone and otacoid-structured drugs. | 16, 19, 9 | A |
| 4.2. interpret the structure activity relationships of the sex hormones. | 16, 19, 9 | A |
| 4.3. interpret the structure activity relationships of the antihistaminic drugs. | 16, 19, 9 | A |
| 4.4. illustrate the synthetic methods of the hormones and otacoids | 16, 19, 9 | A |
| Teaching Methods: | 16: Question - Answer Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Direct and indirect sympathomimetics and sympatholytics. | 1 |
| 2 | Direct and indirect parasympathomimetics and parasympatholytics. | 1 |
| 3 | Drugs used in heart failure, antiarrhythmics and antiallergens. | 1 |
| 4 | Calcium channel blockers, peripheric vasodilators and adrenergic receptor blockers. | 1 |
| 5 | Hemostatics, anticoagulants, antithrombolytics and antianemics. | 1 |
| 6 | Arterial and venous vasodilators, drugs acting on vascular smooth muscle and direckt acting vasodilators. | 1 |
| 7 | drugs acting on renin-angiotensin system. | 1 |
| 8 | Diuretics and antihyperlipidemic drugs. | 1 |
| 9 | Digestants, antiulcer agents, emetic and amtiemetics, laxatives and antidiarrheals. | 1 |
| 10 | Thyroid and peptide hormones and antidiabetics. | 1 |
| 11 | Sex hormones. | 1 |
| 12 | Adrenocorticoids. | 1 |
| 13 | Antihistaminics | 1 |
| 14 | Radiocontrasts, vitamine and immunomodulators. | 1 |
| Resources |
| Pharmaceutical chemistry III notes will be given to the students. |
| 1. Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı Öğretim Üyeleri. (2004) Farmasötik Kimya. Hacettepe Üniversitesi Yayınları, Ankara. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |