Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACOKINETIC and CLINICAL PHARMACOKINETIC | - | Spring Semester | 2+0 | 2 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Çağlar MACİT |
| Name of Lecturer(s) | Assist.Prof. Çağlar MACİT |
| Assistant(s) | |
| Aim | It aims to teach students the importance, principles, steps, and factors that change the pharmacokinetics of drugs in drug research. |
| Course Content | This course contains; History of pharmacokinetic,Importance of pharmacokinetic in clinical trials,Formulas that used in pharmacokinetic calculations,Absorption and factors that affect it,Distribution and factors that affect it,Metabolism and factors that affect it,Elimination and factors that affect it,Pharmacokinetic in children,Pharmacokinetic in elderly,Pharmacokinetic in pregnanancy and lactation ,Pharmacokinetic in patients with liver failure,Pharmacokinetic in patients with kidney failure,Nutrient-Drug, Drug-Drug and Supportive therapy-Drug interactions,Effects of supportive therapy to drug pharmacokinetic . |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Know the steps of pharmacokinetics. | 14, 9 | E |
| Explain what pharmacokinetics is. | 14, 9 | E |
| Know the importance of pharmacokinetics. | 14, 9 | E |
| Know the factors that affect the pharmacokinetics. | 14, 9 | E |
| Know the importance of pharmacokinetics when using drugs in the clinics. | 14, 9 | E |
| Know and evaluate that the pharmacokinetics of drugs may vary in special populations. | 14, 9 | E |
| Teaching Methods: | 14: Self Study Method, 9: Lecture Method |
| Assessment Methods: | E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | History of pharmacokinetic | 1, 2 |
| 2 | Importance of pharmacokinetic in clinical trials | 1, 2 |
| 3 | Formulas that used in pharmacokinetic calculations | 1, 2 |
| 4 | Absorption and factors that affect it | 1, 2 |
| 5 | Distribution and factors that affect it | 1, 2 |
| 6 | Metabolism and factors that affect it | 1, 2 |
| 7 | Elimination and factors that affect it | 1, 2 |
| 8 | Pharmacokinetic in children | 1, 2 |
| 9 | Pharmacokinetic in elderly | 1, 2 |
| 10 | Pharmacokinetic in pregnanancy and lactation | 1, 2 |
| 11 | Pharmacokinetic in patients with liver failure | 1, 2 |
| 12 | Pharmacokinetic in patients with kidney failure | 1, 2 |
| 13 | Nutrient-Drug, Drug-Drug and Supportive therapy-Drug interactions | 1, 2 |
| 14 | Effects of supportive therapy to drug pharmacokinetic | 1, 2 |
| Resources |
| 1. Applied Biopharmaceutics and Pharmacokinetics, 7th edition, Leon Shargel, Andrew B.C. Yu 2. Basic Pharmacokinetics, 2nd edition, Sunil S. Jambhekar, Philip J. Breen |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PY-1.Develops, deepens and deepens innovation in the fields of Clinical pharmacy based on master's qualifications with original thought and research at the level of expertise. | X | |||||
| 2 | PY-2.Interdisciplinary interaction with the field is related to; Reaching original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. | X | |||||
| 3 | PY-3.Has advanced knowledge about the other technological tools including computer and the devices and tools which are specific to the field at the level required by the field. | X | |||||
| 4 | PY-4.Has knowledge about statistical methods. Evaluates and uses new information in the field with a systematic approach. | X | |||||
| 5 | PY-5. Has the advanced knowledge of creating patient profiles, patient education, and medication counseling. | X | |||||
| 6 | PY-6.Write the report of the researcher / participant. National / internationally accepted publications are published at scientific meetings. | X | |||||
| 7 | PY-7.Performs necessary examinations using other technological tools including computer and the devices and tools specific to the field at the advanced level as required by the field; Develop new creative solutions to problems. | X | |||||
| 8 | PY-8.Develop a new idea, method, design or practice that brings innovation to the field, or researches, designs, adapts and applies a known idea, method, design or application that applies to a different field. | X | |||||
| 9 | PY-9. Uses the knowledge and equipment related to administering medicine to patients and the use of the drug. Gives pharmaceutical care service by providing rational and safe drug use with the duty of observance and supervision. | X | |||||
| 10 | PY-10. Acquires administrative and technical stand-by equipment in the areas where the clinical pharmacy is responsible for and achieves hospital pharmacy practices properly. | X | |||||
| 11 | PY-11.Develop new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | X | |||||
| 12 | PY-12. Demonstrates embarking on lifelong learning, open for improvement, and continue this behavior. | X | |||||
| 13 | PY-13.Selects the correct statistical methods in the field of health care work and applies and interprets. | X | |||||
| 14 | PY-14. Has sufficient consciousness in the field of individual and public health, environmental protection, and job security and applies it. | X | |||||
| 15 | PY-15. Informs relevant persons and institutions in the fields of quality assurance of pharmaceutical products. | X | |||||
| 16 | PY-16. Contributes to the solution of scientific, cultural, and ethical problems encountered in the field of clinical pharmacy and corroborates the improvement of these values. Behaves according to the legislation and professional ethics related to duty, right, and responsibilities as an individual. | X | |||||
| 17 | PY-17. Safely documents and keeps track of professional activities and practices. | X | |||||
| 18 | PY-18. Provides information to the patience, healthcare personnel, and society on every drug-related issue. | X | |||||
| 19 | PY-19. Follows and evaluates national and international developments in the field of clinical pharmacy. | X | |||||
| 20 | PY-20.Analyzes statistically to evaluate a scientific article. | X | |||||
| 21 | PY-21.Broaden the boundaries of information in the field by publishing at least one scientific article related to the field in national and / or internationally eminent journals. | X | |||||
| 22 | PY-22.Contributes to the advancement of the field by bringing innovation to the field, developing a new idea, method, design or application, or performing an original study independently applying a known idea, method, design or application to a different field. | X | |||||
| 23 | PY-23. Plans, manages, watches the process, and evaluates activities that oriented improvements of employees as part of a project. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 14 | 4 | 56 | |||
| Resolution of Homework Problems and Submission as a Report | 4 | 8 | 32 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 4 | 16 | 64 | |||
| General Exam | 4 | 16 | 64 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 244 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(244/30) | 8 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACOKINETIC and CLINICAL PHARMACOKINETIC | - | Spring Semester | 2+0 | 2 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Çağlar MACİT |
| Name of Lecturer(s) | Assist.Prof. Çağlar MACİT |
| Assistant(s) | |
| Aim | It aims to teach students the importance, principles, steps, and factors that change the pharmacokinetics of drugs in drug research. |
| Course Content | This course contains; History of pharmacokinetic,Importance of pharmacokinetic in clinical trials,Formulas that used in pharmacokinetic calculations,Absorption and factors that affect it,Distribution and factors that affect it,Metabolism and factors that affect it,Elimination and factors that affect it,Pharmacokinetic in children,Pharmacokinetic in elderly,Pharmacokinetic in pregnanancy and lactation ,Pharmacokinetic in patients with liver failure,Pharmacokinetic in patients with kidney failure,Nutrient-Drug, Drug-Drug and Supportive therapy-Drug interactions,Effects of supportive therapy to drug pharmacokinetic . |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Know the steps of pharmacokinetics. | 14, 9 | E |
| Explain what pharmacokinetics is. | 14, 9 | E |
| Know the importance of pharmacokinetics. | 14, 9 | E |
| Know the factors that affect the pharmacokinetics. | 14, 9 | E |
| Know the importance of pharmacokinetics when using drugs in the clinics. | 14, 9 | E |
| Know and evaluate that the pharmacokinetics of drugs may vary in special populations. | 14, 9 | E |
| Teaching Methods: | 14: Self Study Method, 9: Lecture Method |
| Assessment Methods: | E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | History of pharmacokinetic | 1, 2 |
| 2 | Importance of pharmacokinetic in clinical trials | 1, 2 |
| 3 | Formulas that used in pharmacokinetic calculations | 1, 2 |
| 4 | Absorption and factors that affect it | 1, 2 |
| 5 | Distribution and factors that affect it | 1, 2 |
| 6 | Metabolism and factors that affect it | 1, 2 |
| 7 | Elimination and factors that affect it | 1, 2 |
| 8 | Pharmacokinetic in children | 1, 2 |
| 9 | Pharmacokinetic in elderly | 1, 2 |
| 10 | Pharmacokinetic in pregnanancy and lactation | 1, 2 |
| 11 | Pharmacokinetic in patients with liver failure | 1, 2 |
| 12 | Pharmacokinetic in patients with kidney failure | 1, 2 |
| 13 | Nutrient-Drug, Drug-Drug and Supportive therapy-Drug interactions | 1, 2 |
| 14 | Effects of supportive therapy to drug pharmacokinetic | 1, 2 |
| Resources |
| 1. Applied Biopharmaceutics and Pharmacokinetics, 7th edition, Leon Shargel, Andrew B.C. Yu 2. Basic Pharmacokinetics, 2nd edition, Sunil S. Jambhekar, Philip J. Breen |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PY-1.Develops, deepens and deepens innovation in the fields of Clinical pharmacy based on master's qualifications with original thought and research at the level of expertise. | X | |||||
| 2 | PY-2.Interdisciplinary interaction with the field is related to; Reaching original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. | X | |||||
| 3 | PY-3.Has advanced knowledge about the other technological tools including computer and the devices and tools which are specific to the field at the level required by the field. | X | |||||
| 4 | PY-4.Has knowledge about statistical methods. Evaluates and uses new information in the field with a systematic approach. | X | |||||
| 5 | PY-5. Has the advanced knowledge of creating patient profiles, patient education, and medication counseling. | X | |||||
| 6 | PY-6.Write the report of the researcher / participant. National / internationally accepted publications are published at scientific meetings. | X | |||||
| 7 | PY-7.Performs necessary examinations using other technological tools including computer and the devices and tools specific to the field at the advanced level as required by the field; Develop new creative solutions to problems. | X | |||||
| 8 | PY-8.Develop a new idea, method, design or practice that brings innovation to the field, or researches, designs, adapts and applies a known idea, method, design or application that applies to a different field. | X | |||||
| 9 | PY-9. Uses the knowledge and equipment related to administering medicine to patients and the use of the drug. Gives pharmaceutical care service by providing rational and safe drug use with the duty of observance and supervision. | X | |||||
| 10 | PY-10. Acquires administrative and technical stand-by equipment in the areas where the clinical pharmacy is responsible for and achieves hospital pharmacy practices properly. | X | |||||
| 11 | PY-11.Develop new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | X | |||||
| 12 | PY-12. Demonstrates embarking on lifelong learning, open for improvement, and continue this behavior. | X | |||||
| 13 | PY-13.Selects the correct statistical methods in the field of health care work and applies and interprets. | X | |||||
| 14 | PY-14. Has sufficient consciousness in the field of individual and public health, environmental protection, and job security and applies it. | X | |||||
| 15 | PY-15. Informs relevant persons and institutions in the fields of quality assurance of pharmaceutical products. | X | |||||
| 16 | PY-16. Contributes to the solution of scientific, cultural, and ethical problems encountered in the field of clinical pharmacy and corroborates the improvement of these values. Behaves according to the legislation and professional ethics related to duty, right, and responsibilities as an individual. | X | |||||
| 17 | PY-17. Safely documents and keeps track of professional activities and practices. | X | |||||
| 18 | PY-18. Provides information to the patience, healthcare personnel, and society on every drug-related issue. | X | |||||
| 19 | PY-19. Follows and evaluates national and international developments in the field of clinical pharmacy. | X | |||||
| 20 | PY-20.Analyzes statistically to evaluate a scientific article. | X | |||||
| 21 | PY-21.Broaden the boundaries of information in the field by publishing at least one scientific article related to the field in national and / or internationally eminent journals. | X | |||||
| 22 | PY-22.Contributes to the advancement of the field by bringing innovation to the field, developing a new idea, method, design or application, or performing an original study independently applying a known idea, method, design or application to a different field. | X | |||||
| 23 | PY-23. Plans, manages, watches the process, and evaluates activities that oriented improvements of employees as part of a project. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |